Dr. Edward Ginns, Professor and Director of the Lysosomal Disorders Treatment and Research Program at University of Massachusetts Medical School, Worcester, MA, is board certified in Neurology. He earned his medical degree from Johns Hopkins School of Medicine and completed Neurology residency at Albert Einstein College of Medicine, NY. After residency, he joined Drs. Brady and Barranger at the Developmental and Metabolic Neurology Branch, NIH and worked on development of enzyme replacement for Gaucher disease. In the following years, Dr. Ginns’ team isolated the human glucocerebrosidase gene, identified the N370S and L444P Gaucher mutations and generated Gaucher mouse models. He has co-authored over 150 publications on lysosomal/neurogenetic disorders. His current research continues (i) to characterize the striatal synaptic dysfunction of Gaucher associated Parkinson disease and (ii) a bench to bedside approach to bring orally delivered gene/enzyme therapy for Gaucher disease into clinical trial.